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Bruce & Co., Inc.
Msd Partners, l.p.
Knoll Capital Management, LLC
Atika Capital Management LLC
Alethea Capital Management, LLC
Lilly Endowment Inc
Ikarian Capital, LLC
Cpmg Inc
Fairmount Funds Management LLC
Pathway Capital Management, Lp
Foresite Capital Management Iv, LLC
Ghost Tree Capital, LLC
Stonepine Capital Management, LLC
Sector Gamma As
Chi Advisors LLC
Krensavage Asset Management, LLC
Robert Wood Johnson Foundation
Great Point Partners LLC
Birchview Capital, Lp
Ridgeback Capital Investments l.p.
Psquared Asset Management Ag
International Biotechnology Trust Plc
Sarissa Capital Management Lp
Avoro Capital Advisors LLC
Healthcor Management, l.p.
Finepoint Capital Lp
Rp Management, LLC
Sivik Global Healthcare LLC
Venbio Partners LLC
Sofinnova Investments, Inc.
Tekla Capital Management LLC
Logos Global Management Lp
Rhenman & Partners Asset Management Ab
Abingworth LLP
Iron Triangle Partners Lp
Soleus Capital Management, l.p.
Prosight Management, Lp
Pentwater Capital Management Lp
Sectoral Asset Management Inc
Meditor Group Ltd
Sio Capital Management, LLC
Eversept Partners, Lp
Sphera Funds Management Ltd.
Integral Health Asset Management, LLC
Palo Alto Investors Lp
Harvest Management LLC
Bellevue Group Ag
Virtus ETF Advisers LLC
Trv Gp Iii, LLC
Avidity Partners Management Lp