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Flagship Pioneering Inc.
Pura Vida Investments, LLC
Lilly Endowment Inc
Aviva Holdings Ltd.
Vivo Capital, LLC
First Light Asset Management, LLC
Foresite Capital Management Ii, LLC
Avoro Capital Advisors LLC
Pfm Health Sciences, Lp
Acuta Capital Partners, LLC
Viking Global Investors Lp
Lumina Fund Management LLC
Prosight Management, Lp
Ghost Tree Capital, LLC
Suvretta Capital Management, LLC
Eversept Partners, Lp
Highvista Strategies LLC
Dafna Capital Management LLC
Tamarack Advisers, Lp
Greenleaf Trust
Bvf Inc/il
Bruce & Co., Inc.
Sarissa Capital Management Lp
Baker Bros. Advisors Lp
Ecor1 Capital, LLC
Versant Venture Management, LLC
Bellevue Group Ag
Mcadam, LLC
Biondo Investment Advisors, LLC
Endurant Capital Management Lp
Sector Gamma As
Healthcor Management, l.p.
Redmile Group, LLC
Aquilo Capital Management, LLC
Great Point Partners LLC
Sofinnova Investments, Inc.
Harvard Management Co Inc
Casdin Capital, LLC
Heritage Wealth Advisors
Appleton Group, LLC
Oracle Investment Management Inc
Rhenman & Partners Asset Management Ab
Opaleye Management Inc.
Krensavage Asset Management, LLC
Tekla Capital Management LLC
Sym Financial Corp
Alethea Capital Management, LLC
Orbimed Advisors LLC
Boxer Capital, LLC
New Leaf Venture Partners, l.l.c.
Sabby Management, LLC
Rock Springs Capital Management Lp
Sio Capital Management, LLC
Palo Alto Investors Lp
Cpmg Inc
Foresite Capital Management Iii, LLC
Rtw Investments, Lp
Rainey & Randall Investment Management Inc.
Robert Wood Johnson Foundation
Trv Gp Ii, LLC
Cormorant Asset Management, Lp
International Biotechnology Trust Plc
Sectoral Asset Management Inc
Perceptive Advisors LLC
Sphera Funds Management Ltd.
Wilshire Advisors LLC
Summit Rock Advisors, Lp
Summer Road LLC
Knoll Capital Management, LLC
Nea Management Company, LLC
Foresite Capital Management Iv, LLC
Consonance Capital Management Lp
Sivik Global Healthcare LLC
Rubric Capital Management Lp
Chubb Ltd
Armistice Capital, LLC
Tradelink Capital LLC
Copernicus Capital Management, LLC
Polaris Venture Management Co. v, l.l.c.
Asymmetry Capital Management, l.p.
Starr International Co Inc
Meditor Group Ltd
Northwestern University
Bain Capital Life Sciences Investors, LLC
Birchview Capital, Lp
Stonepine Capital Management, LLC
Virtus ETF Advisers LLC
Omega Fund Management, LLC
Caxton Corp
Third Security, LLC
Trv Gp Iii, LLC
Rho Capital Partners Inc
Sv Health Investors, LLC
Artal Group s.a.
Tpg Group Holdings (Sbs) Advisors, Inc.
Healthcare Value Capital, LLC
Mpm Asset Management LLC
Interwest Venture Management Co
Atlas Venture Associates Ix, LLC
Tang Capital Management LLC