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Flagship Pioneering Inc.
Lilly Endowment Inc
First Light Asset Management, LLC
Polaris Venture Management Co. v, l.l.c.
Foresite Capital Management Ii, LLC
Vivo Capital, LLC
Aviva Holdings Ltd.
Dafna Capital Management LLC
Pfm Health Sciences, Lp
Aquilo Capital Management, LLC
Lumina Fund Management LLC
Sivik Global Healthcare LLC
Avoro Capital Advisors LLC
Cpmg Inc
Baker Bros. Advisors Lp
Prosight Management, Lp
Leith Wheeler Investment Counsel Ltd.
Tamarack Advisers, Lp
Bellevue Group Ag
Sabby Management, LLC
Ghost Tree Capital, LLC
Highvista Strategies LLC
Sector Gamma As
Eversept Partners, Lp
Alethea Capital Management, LLC
Sarissa Capital Management Lp
Greenleaf Trust
Redmile Group, LLC
Trv Gp, LLC
Bvf Inc/il
Harvard Management Co Inc
Rtw Investments, Lp
Healthcor Management, l.p.
Casdin Capital, LLC
Sofinnova Investments, Inc.
Acuta Capital Partners, LLC
Rhenman & Partners Asset Management Ab
Farallon Capital Management LLC
Boxer Capital, LLC
Opaleye Management Inc.
Sio Capital Management, LLC
Orbimed Advisors LLC
Rock Springs Capital Management Lp
Cormorant Asset Management, Lp
Oracle Investment Management Inc
Great Point Partners LLC
Mcadam, LLC
Tekla Capital Management LLC
Robert Wood Johnson Foundation
Ecor1 Capital, LLC
Plancorp, LLC
Appleton Group, LLC
Heritage Wealth Advisors
New Leaf Venture Partners, l.l.c.
Versant Venture Management, LLC
Nea Management Company, LLC
Asymmetry Capital Management, l.p.
Bruce & Co., Inc.
Sym Financial Corp
Palo Alto Investors Lp
Perceptive Advisors LLC
Summer Road LLC
Stonepine Capital Management, LLC
Sphera Funds Management Ltd.
International Biotechnology Trust Plc
Northwestern University
Krensavage Asset Management, LLC
Consonance Capital Management Lp
Foresite Capital Management Iii, LLC
Sectoral Asset Management Inc
Hudson Capital Management LLC
General Atlantic, l.p.
Bain Capital Life Sciences Investors, LLC
Birchview Capital, Lp
Third Security, LLC
Caxton Corp
Healthcare Value Capital, LLC
Armistice Capital, LLC
Clayton, Dubilier & Rice, LLC
Deerfield Management Company, l.p. (Series C)
New Mountain Vantage Advisers, l.l.c.
Garnet Equity Capital Holdings, Inc.
Mason Capital Management LLC
Endurant Capital Management Lp
Summit Rock Advisors, Lp
Trv Gp Ii, LLC
Courage Capital Management LLC
Pura Vida Investments, LLC
Copernicus Capital Management, LLC
Summit Partners L P
Foresite Capital Management Iv, LLC
Knoll Capital Management, LLC
Sv Health Investors, LLC
Virtus ETF Advisers LLC
Atlas Venture Associates Ix, LLC
Mpm Asset Management LLC
Omega Fund Management, LLC
Meditor Group Ltd
Starr International Co Inc
Interwest Venture Management Co