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Armistice Capital, LLC
Ghost Tree Capital, LLC
Maso Capital Partners Ltd
Aviva Holdings Ltd.
Pura Vida Investments, LLC
First Light Asset Management, LLC
Avoro Capital Advisors LLC
Battery Partners Ix, LLC
Regents of the University of California
Foresite Capital Management Ii, LLC
Ra Capital Management, l.p.
Boxer Capital, LLC
Vivo Capital, LLC
Casdin Capital, LLC
Broadwood Capital Inc
Opaleye Management Inc.
Acuta Capital Partners, LLC
Alethea Capital Management, LLC
Flagship Pioneering Inc.
Lilly Endowment Inc
Dafna Capital Management LLC
Cormorant Asset Management, Lp
Bridger Management, LLC
Baker Bros. Advisors Lp
Sb Investment Advisers (Uk) Ltd
Sabby Management, LLC
Deerfield Management Company, l.p. (Series C)
Bvf Inc/il
Orbimed Advisors LLC
Nantahala Capital Management, LLC
Pfm Health Sciences, Lp
Js Capital Management LLC
Hellman Jordan Management Co Inc /ma/
Eventide Asset Management, LLC
Redmile Group, LLC
Asymmetry Capital Management, l.p.
Rtw Investments, Lp
New Leaf Venture Partners, l.l.c.
Perceptive Advisors LLC
Oracle Investment Management Inc
Sivik Global Healthcare LLC
Great Point Partners LLC
Polaris Venture Management Co. v, l.l.c.
Harvard Management Co Inc
Rhenman & Partners Asset Management Ab
Greenleaf Trust
Bellevue Group Ag
Ecor1 Capital, LLC
Rock Springs Capital Management Lp
Sector Gamma As