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Armistice Capital, LLC
Flagship Pioneering Inc.
Pura Vida Investments, LLC
Polaris Venture Management Co. v, l.l.c.
Trv Gp, LLC
Foresite Capital Management Ii, LLC
Lilly Endowment Inc
First Light Asset Management, LLC
Aviva Holdings Ltd.
Vivo Capital, LLC
Dafna Capital Management LLC
Aquilo Capital Management, LLC
Avoro Capital Advisors LLC
Cpmg Inc
Copernicus Capital Management, LLC
New Mountain Vantage Advisers, l.l.c.
Sabby Management, LLC
Alethea Capital Management, LLC
Lumina Fund Management LLC
Ghost Tree Capital, LLC
Pfm Health Sciences, Lp
Baker Bros. Advisors Lp
Garnet Equity Capital Holdings, Inc.
Prosight Management, Lp
Oracle Investment Management Inc
Rtw Investments, Lp
Sivik Global Healthcare LLC
Casdin Capital, LLC
Acuta Capital Partners, LLC
Bellevue Group Ag
Tamarack Advisers, Lp
Sarissa Capital Management Lp
Bvf Inc/il
Leith Wheeler Investment Counsel Ltd.
Redmile Group, LLC
Deerfield Management Company, l.p. (Series C)
Eversept Partners, Lp
Sofinnova Investments, Inc.
Opaleye Management Inc.
Summer Road LLC
Greenleaf Trust
Sector Gamma As
Boxer Capital, LLC
New Leaf Venture Partners, l.l.c.
Versant Venture Management, LLC
Harvard Management Co Inc
Rhenman & Partners Asset Management Ab
Cormorant Asset Management, Lp
Highvista Strategies LLC
Healthcor Management, l.p.