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Armistice Capital, LLC
Lion Point Capital, Lp
Ghost Tree Capital, LLC
Aviva Holdings Ltd.
Pura Vida Investments, LLC
Polaris Venture Management Co. v, l.l.c.
First Light Asset Management, LLC
Flagship Pioneering Inc.
Avoro Capital Advisors LLC
Crestline Management, Lp
Vivo Capital, LLC
Sc Us (Ttgp), Ltd.
New Leaf Venture Partners, l.l.c.
Opaleye Management Inc.
Ra Capital Management, l.p.
Dafna Capital Management LLC
Boxer Capital, LLC
Summer Road LLC
Versant Venture Management, LLC
Trv Gp, LLC
Redmile Group, LLC
Regents of the University of California
Orbimed Advisors LLC
Copernicus Capital Management, LLC
Casdin Capital, LLC
Rtw Investments, Lp
Kite Lake Capital Management (Uk) LLP
Lilly Endowment Inc
Acuta Capital Partners, LLC
Baker Bros. Advisors Lp
Foresite Capital Management Ii, LLC
Bain Capital Life Sciences Investors, LLC
Bridger Management, LLC
Rho Capital Partners Inc
Cormorant Asset Management, Lp
Asymmetry Capital Management, l.p.
Bvf Inc/il
Deerfield Management Company, l.p. (Series C)
Eventide Asset Management, LLC
Sabby Management, LLC
Foresite Capital Management Iv, LLC
Alethea Capital Management, LLC
Eversept Partners, Lp
Perceptive Advisors LLC
Pfm Health Sciences, Lp
Oracle Investment Management Inc
Harvard Management Co Inc
Omega Fund Management, LLC
Bellevue Group Ag
Rock Springs Capital Management Lp