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  • Trv Gp, LLC
  • Sabby Management, LLC
  • General Atlantic LLC
  • Knoll Capital Management, Lp
  • Sc Us (Ttgp), Ltd.
  • Lion Point Capital, Lp
  • Tamarack Advisers, Lp
  • Calton & Associates, Inc.
  • Greenleaf Trust
  • Crestline Management, Lp
  • Knott David M
  • Kingdon Capital Management, l.l.c.
  • Mcadam, LLC
  • Kite Lake Capital Management (Uk) LLP
  • Heritage Wealth Advisors
  • Virtus ETF Advisers LLC
  • Agf Investments LLC
  • Essex Woodlands Management, Inc.
  • Mivtachim the Workers Social Insurance Fund Ltd. (Under Special Management)
  • Aviva Holdings Ltd.
  • Prosight Management, Lp
  • Bruce & Co., Inc.
  • Bridgeworth, LLC
  • Rho Capital Partners Inc
  • Mv Capital Management, Inc.
  • Caxton Corp
  • Summit Rock Advisors, Lp
  • Harbourvest Partners LLC
  • Chubb Ltd
  • Meditor Group Ltd
  • Nea Management Company, LLC
  • Interwest Venture Management Co
  • Atlas Venture Associates Ix, LLC
  • Polaris Venture Management Co. v, l.l.c.
  • Healthcare Value Capital, LLC
  • Eventide Asset Management, LLC
  • Sv Health Investors, LLC
  • Biondo Investment Advisors, LLC
  • Highvista Strategies LLC
  • Armistice Capital, LLC
  • Abingworth LLP
  • Sarissa Capital Management Lp
  • Stonepine Capital Management, LLC
  • Ulys, l.l.c.
  • Oracle Investment Management Inc
  • Bridger Management, LLC
  • Pura Vida Investments, LLC
  • Sio Capital Management, LLC
  • Neumann Capital Management, LLC
  • Robert Wood Johnson Foundation