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Lilly Endowment Inc
Flagship Pioneering Inc.
Pura Vida Investments, LLC
Pfm Health Sciences, Lp
Highvista Strategies LLC
Suvretta Capital Management, LLC
First Light Asset Management, LLC
Bruce & Co., Inc.
Vivo Capital, LLC
Copernicus Capital Management, LLC
Viking Global Investors Lp
Lumina Fund Management LLC
Aviva Holdings Ltd.
Polaris Venture Management Co. v, l.l.c.
Greenleaf Trust
Acuta Capital Partners, LLC
Avoro Capital Advisors LLC
Tamarack Advisers, Lp
Foresite Capital Management Ii, LLC
Prosight Management, Lp
Mcadam, LLC
Eversept Partners, Lp
Appleton Group, LLC
Sector Gamma As
Healthcor Management, l.p.
Endurant Capital Management Lp
Sarissa Capital Management Lp
Biondo Investment Advisors, LLC
Heritage Wealth Advisors
Ghost Tree Capital, LLC
Ecor1 Capital, LLC
Bellevue Group Ag
Krensavage Asset Management, LLC
Baker Bros. Advisors Lp
Tekla Capital Management LLC
Harvard Management Co Inc
Bvf Inc/il
Dafna Capital Management LLC
Robert Wood Johnson Foundation
Asymmetry Capital Management, l.p.
Sio Capital Management, LLC
Rainey & Randall Investment Management Inc.
Sivik Global Healthcare LLC
Great Point Partners LLC
Rhenman & Partners Asset Management Ab
Redmile Group, LLC
Chubb Ltd
Aquilo Capital Management, LLC
Sofinnova Investments, Inc.
Sym Financial Corp