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  • Lilly Endowment Inc
  • Pura Vida Investments, LLC
  • First Light Asset Management, LLC
  • Sivik Global Healthcare LLC
  • Pfm Health Sciences, Lp
  • Highvista Strategies LLC
  • Flagship Pioneering Inc.
  • Garnet Equity Capital Holdings, Inc.
  • Copernicus Capital Management, LLC
  • Lumina Fund Management LLC
  • Foresite Capital Management Ii, LLC
  • Sector Gamma As
  • Vivo Capital, LLC
  • Healthcor Management, l.p.
  • Leith Wheeler Investment Counsel Ltd.
  • Dafna Capital Management LLC
  • Polaris Venture Management Co. v, l.l.c.
  • Greenleaf Trust
  • Robert Wood Johnson Foundation
  • Tamarack Advisers, Lp
  • Appleton Group, LLC
  • Mcadam, LLC
  • Aviva Holdings Ltd.
  • Prosight Management, Lp
  • Harvard Management Co Inc
  • Farallon Capital Management LLC
  • Sio Capital Management, LLC
  • Bellevue Group Ag
  • Bruce & Co., Inc.
  • Aquilo Capital Management, LLC
  • Sarissa Capital Management Lp
  • Tekla Capital Management LLC
  • Deerfield Management Company, l.p. (Series C)
  • Eversept Partners, Lp
  • Baker Bros. Advisors Lp
  • Cpmg Inc
  • New Mountain Vantage Advisers, l.l.c.
  • Heritage Wealth Advisors
  • Plancorp, LLC
  • Avoro Capital Advisors LLC
  • Redmile Group, LLC
  • Rhenman & Partners Asset Management Ab
  • Bvf Inc/il
  • Sofinnova Investments, Inc.
  • Rock Springs Capital Management Lp
  • Alethea Capital Management, LLC
  • Rtw Investments, Lp
  • Ghost Tree Capital, LLC
  • Acuta Capital Partners, LLC
  • Great Point Partners LLC