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  • Pura Vida Investments, LLC
  • First Light Asset Management, LLC
  • Aviva Holdings Ltd.
  • Pfm Health Sciences, Lp
  • Sivik Global Healthcare LLC
  • Lilly Endowment Inc
  • Highvista Strategies LLC
  • Avoro Capital Advisors LLC
  • Newfound Research LLC
  • Js Capital Management LLC
  • Ra Capital Management, l.p.
  • Battery Partners Ix, LLC
  • Bridger Management, LLC
  • Asymmetry Capital Management, l.p.
  • Deerfield Management Company, l.p. (Series C)
  • Hellman Jordan Management Co Inc /ma/
  • Boxer Capital, LLC
  • Greenleaf Trust
  • Sector Gamma As
  • Redmile Group, LLC
  • Harvard Management Co Inc
  • Orbimed Advisors LLC
  • Opaleye Management Inc.
  • Broadwood Capital Inc
  • Dafna Capital Management LLC
  • Yale University
  • Vivo Capital, LLC
  • Baker Bros. Advisors Lp
  • Bvf Inc/il
  • Foresite Capital Management Ii, LLC
  • Sio Capital Management, LLC
  • Casdin Capital, LLC
  • Great Point Partners LLC
  • Eventide Asset Management, LLC
  • Acuta Capital Partners, LLC
  • Cormorant Asset Management, Lp
  • Chubb Ltd
  • Farallon Capital Management LLC
  • Nantahala Capital Management, LLC
  • Alethea Capital Management, LLC
  • Agf Investments LLC
  • Rhenman & Partners Asset Management Ab
  • Kingdon Capital Management, l.l.c.
  • Bellevue Group Ag
  • Perceptive Advisors LLC
  • Rtw Investments, Lp
  • Healthcor Management, l.p.
  • Rock Springs Capital Management Lp
  • Regents of the University of California
  • Fc Advisory LLC