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Lilly Endowment Inc
Baker Bros. Advisors Lp
Bellevue Group Ag
Greenleaf Trust
Orbimed Advisors LLC
Vivo Capital, LLC
Avoro Capital Advisors LLC
Armistice Capital, LLC
Rtw Investments, Lp
Hhlr Advisors, Ltd.
Perceptive Advisors LLC
Flagship Pioneering Inc.
Rock Springs Capital Management Lp
Nea Management Company, LLC
New Mountain Vantage Advisers, l.l.c.
Suvretta Capital Management, LLC
Redmile Group, LLC
Ecor1 Capital, LLC
Pura Vida Investments, LLC
Tekla Capital Management LLC
Pfm Health Sciences, Lp
Bvf Inc/il
Artal Group s.a.
Robert Wood Johnson Foundation
Casdin Capital, LLC
Boxer Capital, LLC
Novo Holdings A/s
Healthcor Management, l.p.
Sofinnova Investments, Inc.
Cormorant Asset Management, Lp
Palo Alto Investors Lp
First Light Asset Management, LLC
Eversept Partners, Lp
Sarissa Capital Management Lp
Mcadam, LLC
Bain Capital Life Sciences Investors, LLC
Rhenman & Partners Asset Management Ab
Harvard Management Co Inc
Kingdon Capital Management, l.l.c.
Sphera Funds Management Ltd.
Berkshire Money Management, Inc.
Aquilo Capital Management, LLC
Regents of the University of California
Cpmg Inc
Sectoral Asset Management Inc
Oracle Investment Management Inc
Tang Capital Management LLC
Bruce & Co., Inc.
Omega Fund Management, LLC
Sabby Management, LLC