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  • Armistice Capital, LLC
  • Ghost Tree Capital, LLC
  • Sphera Funds Management Ltd.
  • Sabby Management, LLC
  • Pura Vida Investments, LLC
  • First Light Asset Management, LLC
  • Foresite Capital Management Ii, LLC
  • Casdin Capital, LLC
  • Opaleye Management Inc.
  • Boxer Capital, LLC
  • Versant Venture Management, LLC
  • Avoro Capital Advisors LLC
  • Dafna Capital Management LLC
  • Bvf Inc/il
  • Rtw Investments, Lp
  • Perceptive Advisors LLC
  • Redmile Group, LLC
  • Vivo Capital, LLC
  • New Leaf Venture Partners, l.l.c.
  • Lilly Endowment Inc
  • Acuta Capital Partners, LLC
  • Ecor1 Capital, LLC
  • Aviva Holdings Ltd.
  • Polaris Venture Management Co. v, l.l.c.
  • Pfm Health Sciences, Lp
  • Palo Alto Investors Lp
  • Great Point Partners LLC
  • Asymmetry Capital Management, l.p.
  • Deerfield Management Company, l.p. (Series C)
  • Foresite Capital Management Iii, LLC
  • Tamarack Advisers, Lp
  • Orbimed Advisors LLC
  • Consonance Capital Management Lp
  • Sivik Global Healthcare LLC
  • Lumina Fund Management LLC
  • New Mountain Vantage Advisers, l.l.c.
  • Rhenman & Partners Asset Management Ab
  • Sarissa Capital Management Lp
  • Baker Bros. Advisors Lp
  • Greenleaf Trust
  • Bellevue Group Ag
  • Cormorant Asset Management, Lp
  • Sector Gamma As
  • Rock Springs Capital Management Lp
  • General Atlantic, l.p.
  • Omega Fund Management, LLC
  • Alethea Capital Management, LLC
  • Healthcor Management, l.p.
  • Leith Wheeler Investment Counsel Ltd.
  • Farallon Capital Management LLC